Lightly pick through crab meat for shells.
Whisk egg in a medium bowl.
Add Worcestershire sauce, Old Bay, mustard, and mayonnaise to the egg. Set aside.
In a separate bowl, add crab meat. Fold the egg mixture into crab meat.
Add panko bread crumbs. Gently mix with hands being careful not to break up lump crab pieces.
Place the crab mixture in the fridge for 30-60 minutes. This really does help hold the crab cakes together.
Preheat oven to 425º.
With clean hands, make 6 crab cakes about 4-inches in diameter.
Bake crab cakes for about 12 minutes or until golden brown on top. Finish with them under the broiler for 2-3 minutes.
Serve with a sauce of your choice or a squeeze of lemon.